Q. Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain?
(a) Lipase
(b) Protease
(c) Exonuclease
(d) Endonuclease
Solution :
Correct option : C Endonucleases hydrolyse internal phosphodiester bonds in a polynucleotide chain. Function of nucleases is to break phosphodiester bond. A nuclease is an enzyme capable of cleaving the phosphodiester bonds between the nucleotide subunits of nucleic acids. Nucleases are usually further divided into endonucleases and exonucleases, although some of the enzymes may fall in both categories.