Q. Which one of the following cannot be used for preparation of vaccination against plague?

Q. Which one of the following cannot be used for preparation of vaccination against plague?

Q. Which one of the following cannot be used for preparation of vaccination against plague?

(a) Avirulent live bacteria

(b) Synthetic capsular polysaccharide material

(c) Heat killed suspension of virulent bacteria

(d) Formalin- inactivated suspension of virulent bacteria

Solution : Correct option : B

  • Plague is an infectious disease caused by the bacterium Yersinia pestis.
  • Killed bacteria have been used since 1890 but are less effective against pneumonic plague so that recently live vaccines of an attenuated type and recombination protein vaccines have been developed to prevent the disease.
  • Synthetic capsular polysaccharide vaccines are used for the treatment of pneumonia and meningitis.
  • Hence, Synthetic capsular polysaccharide material cannot be used for the preparation of vaccination against the plague.

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